It’s one of the favorite weeks NFL fans are thankful for — the Thanksgiving meal and three games on Thanksgiving.

One of the NFL’s top rivalries will resume on Thanksgiving when the New York Giants play at the Dallas Cowboys (4:30 p.m. ET Thursday, FOX and FOX Sports app) in a series that dates to 1960 when the ‘Boys joined the NFL. 

Here’s everything you need to know about the NFL odds for Week 12 — the point spread, moneyline and total Over/Under (with all NFL odds via FOX Bet).

All times ET

THURSDAY’S GAMES

Bills at Lions (12:30 p.m., CBS)

Point spread: Bills -9.5 (Bills favored to win by more than 9.5 points, otherwise Lions cover)
Moneyline: Bills -400 favorites to win (bet $10 to win $12.50 total); Lions +280 underdogs to win (bet $10 to win $38 total)
Total scoring Over/Under: 54.5 points scored by both teams combined

Giants at Cowboys (4:30 p.m., FOX and FOX Sports app)

Point spread: Cowboys -10 (Cowboys favored to win by more than 10 points, otherwise Giants cover)
Moneyline: Cowboys -455 favorites to win (bet $10 to win $12.20 total); Giants +280 underdogs to win (bet $10 to win $38 total)
Total scoring Over/Under: 45.5 points scored by both teams combined

Patriots at Vikings (8:20 p.m., NBC)

Point spread: Vikings -2.5 (Vikings favored to win by more than 2.5 points, otherwise Patriots cover)
Moneyline: Vikings -149 favorites to win (bet $10 to win $16.71 total); Patriots +115 underdogs to win (bet $10 to win $21.50 total)
Total scoring Over/Under: 42.5 points scored by both teams combined

SUNDAY’S GAMES

Buccaneers at Browns (1 p.m., FOX)

Point spread: Buccaneers -3.5 (Buccaneers favored to win by more than 3.5 points, otherwise Browns cover)
Moneyline: Buccaneers -182 favorites to win (bet $10 to win $15.49 total); Browns +140 underdogs to win (bet $10 to win $24 total)
Total scoring Over/Under: 42.5 points scored by both teams combined

Bengals at Titans (1 p.m., CBS)

Point spread: Bengals -2.5 (Bengals favored to win by more than 2.5 points, otherwise Titans cover)
Moneyline: Bengals -143 favorites to win (bet $10 to win $16.99 total); Titans +110 underdogs to win (bet $10 to win $21 total)
Total scoring Over/Under: 42.5 points scored by both teams combined

Texans at Dolphins (1 p.m., CBS)

Point spread: Dolphins -13.5 (Dolphins favored to win by more than 13.5 points, otherwise Texans cover)
Moneyline: Dolphins -667 favorites to win (bet $10 to win $11.50 total); Texans +425 underdogs to win (bet $10 to win $52.50 total)
Total scoring Over/Under: 46.5 points scored by both teams combined

Bears at Jets (1 p.m., FOX)

Point spread: Jets -6 (Jets favored to win by more than 6 points, otherwise Bears cover)
Moneyline: Jets -250 favorites to win (bet $10 to win $14 total); Bears +190 underdogs to win (bet $10 to win $29 total)
Total scoring Over/Under: 38.5 points scored by both teams combined

Falcons at Commanders (1 p.m., FOX)

Point spread: Commanders -4 (Commanders favored to win by more than 4 points, otherwise Falcons cover)
Moneyline: Commanders -213 favorites to win (bet $10 to win $14.69 total); Falcons +160 underdogs to win (bet $10 to win $26 total)
Total scoring Over/Under: 41.5 points scored by both teams combined

Broncos at Panthers (1 p.m., FOX)

Point spread: Broncos -2.5 (Broncos favored to win by more than 2.5 points, otherwise Panthers cover)
Moneyline: Broncos -143 favorites to win (bet $10 to win $16.99 total); Panthers +110 underdogs to win (bet $10 to win $21 total)
Total scoring Over/Under: 36.5 points scored by both teams combined

Ravens at Jaguars (1 p.m., CBS)

Point spread: Ravens -4 (Ravens favored to win by more than 4 points, otherwise Jaguars cover)
Moneyline: Ravens -213 favorites to win (bet $10 to win $14.69 total); Jaguars +160 underdogs to win (bet $10 to win $26 total)
Total scoring Over/Under: 43.5 points scored by both teams combined

Chargers at Cardinals (4:05 p.m., CBS)

Point spread: Chargers -3 (Chargers favored to win by more than 3 points, otherwise Cardinals cover)
Moneyline: Chargers -167 favorites to win (bet $10 to win $15.99 total); Cardinals +130 underdogs to win (bet $10 to win $23 total)
Total scoring Over/Under: 48.5 points scored by both teams combined

Raiders at Seahawks (4:05 p.m., CBS)

Point spread: Seahawks -3.5 (Seahawks favored to win by more than 3.5 points, otherwise Raiders cover)
Moneyline: Seahawks -189 favorites to win (bet $10 to win $15.29 total); Raiders +145 underdogs to win (bet $10 to win $24.50 total)
Total scoring Over/Under: 47.5 points scored by both teams combined

Rams at Chiefs (4:25 p.m., FOX)

Point spread: Chiefs -15.5 (Chiefs favored to win by more than 15.5 points, otherwise Rams cover)
Moneyline: Chiefs -1429 favorites to win (bet $10 to win $10.70 total); Rams +700 underdogs to win (bet $10 to win $80 total)
Total scoring Over/Under: 43.5 points scored by both teams combined

Saints at 49ers (4:25 p.m., FOX)

Point spread: 49ers -8.5 (49ers favored to win by more than 8.5 points, otherwise Saints cover)
Moneyline: 49ers -400 favorites to win (bet $10 to win $12.50 total); Saints +280 underdogs to win (bet $10 to win $38 total)
Total scoring Over/Under: 42.5 points scored by both teams combined

Packers at Eagles (8:20 p.m., NBC)

Point spread: Eagles -6.5 (Eagles favored to win by more than 6.5 points, otherwise Packers cover)
Moneyline: Eagles -303 favorites to win (bet $10 to win $13.30 total); Packers +225 underdogs to win (bet $10 to win $32.50 total)
Total scoring Over/Under: 46.5 points scored by both teams combined

MONDAY’S GAME

Steelers at Colts (8:15 p.m. ET, ESPN)

Point spread: Colts -2.5 (Colts favored to win by more than 2.5 points, otherwise Steelers cover)
Moneyline: Colts -149 favorites to win (bet $10 to win $16.71 total); Steelers +115 underdogs to win (bet $10 to win $21.50 total)
Total scoring Over/Under: 39.5 points scored by both teams combined

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